Dr. Mark Hyman on TODAY: Longevity and Urolithin A

As a 15-time #1 New York Times bestselling author and founder of the Cleveland Clinic Center for Functional Medicine, Dr. Hyman's insights are highly regarded in the health and wellness community.

While discussing healthy aging strategies, Dr. Hyman highlighted the postbiotic Urolithin A as a tool to activate longevity pathways. We are incredibly proud of this recognition at Timeline, as Mitopure®, our advanced Urolithin A supplement, is at the heart of our nutrition and skincare solutions.

Gut Health: The Microbiome's Role in Longevity

During the TODAY Show segment, Dr. Hyman discusses the importance of gut health for longevity.

Dr. Hyman: "Your microbiome is so important now. It's related to almost everything related to heart disease, cancer, diabetes, dementia, even aging itself."

This statement highlights the growing recognition of the gut microbiome as central to overall health and longevity. Dr. Hyman recommends consuming prebiotics (like fiber and polyphenols), probiotics, and postbiotics. These dietary interventions can help maintain a diverse and healthy gut microbiome, supporting various aspects of health and longevity.

Urolithin A: A Powerful Postbiotic for Longevity

Perhaps most notably, Dr. Hyman highlighted the importance of postbiotics, particularly Urolithin A. Postbiotics are active metabolites that our gut microbiota produce, and they confer health benefits across the human body.

"There's a really cool one from pomegranate. The other category of things [prebiotics] is polyphenols, which are colorful plant compounds… the bacteria in your gut transform it into something called Urolithin A, a big medical word, but it activates your longevity pathways."Dr. Mark Hyman

Timeline is the first clinically validated Urolithin A supplement with over 15 years of research and 50 patents backing it’s safety and efficacy. While Dr. Hyman mentions pomegranate as a source of Urolithin A, Mitopure® offers a much more bioavailable form of this powerful postbiotic.

Pomegranate provides only precursors to Urolithin A. The conversion of these precursors to Urolithin A depends on an individual's gut microbiome. Studies have shown that only about 30-40% of people have the right gut bacteria to produce meaningful amounts of Urolithin A from pomegranate. ^[1]

Additionally, you would need to drink 6 cups of pomegranate juice a day, to get the same effect as 500 mg of Mitopure.^[2]

In contrast, Mitopure® is a pure, synthesized form of Urolithin A that doesn't rely on gut conversion. It’s also clinically proven to re-energize cells and^[3] increase muscle strength and endurance[4]. Most importantly, everyone who takes Mitopure® can benefit from Urolithin A, regardless of their gut microbiome composition!

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The Power of Hormesis: Good Stress for Longevity

Dr. Hyman also emphasized the importance of hormesis, or beneficial stress, in promoting longevity:

"We need to stress our bodies. That's how we evolve to get stronger. It's a concept called hormesis, which means the stress basically doesn't kill you, it makes you stronger."Dr. Mark Hyman

This concept is fundamental to understanding how certain lifestyle practices can activate our body's natural defense mechanisms and longevity pathways. Dr. Hyman specifically highlighted the benefits of sauna use:

Dr. Hyman: "Saunas are awesome because saunas actually activate all these incredible longevity pathways. For example, they repair damaged proteins, they boost up your immune system. They help your cardiovascular health."

The remarkable benefits of sauna use underscore the importance of incorporating hormetic stressors into our daily routines. These controlled stressors stimulate our bodies to become more resilient and adaptable without causing fatigue.

Strength Training: The Foundation of Healthy Aging

Dr. Hyman placed significant emphasis on the role of strength training in maintaining health and longevity:

Muscle is the currency of longevity. When you age, you lose muscle. It's called sarcopenia. Muscles are where your metabolism is. If you don't keep your muscle, you're going to age fast.Dr. Mark Hyman

This statement aligns perfectly with Timeline's focus on mitochondrial and muscle health. Mitopure® is clinically proven to improve muscle strength and endurance without increased exercise, directly supporting muscle function.^[5]

These exercise-like effects of Mitopure provide a practical approach to supporting overall health.

Nutrition for Longevity: The Importance of Protein and Healthy Fats

During this interview, Dr. Hyman also stressed the significance of key nutrients for longevity, particularly the roles of protein and healthy fats:

"Fat and protein are key for longevity. First, food is not just calories; it's information. It's medicine… You want protein for breakfast because it activates muscle building, which is important. It activates stem cell healing repair."Dr. Mark Hyman

This advice underscores the importance of viewing food as more than just fuel. Certain nutrients are required for muscle building and stimulating crucial biological processes.

Dr. Hyman's recommendation to start the day with protein-rich meals aligns with current research on the benefits of protein for muscle maintenance and metabolic health.

Wrapping Up

Dr. Hyman's insights on the TODAY Show underscore the growing importance of holistic approaches to longevity, with a special focus on muscle health, nutrition, and innovative supplements like Urolithin A. By integrating these strategies into your daily routine, you can activate your body's natural pathways for a healthier, longer life. At Timeline, we're proud to offer Mitopure®, a clinically validated supplement that aligns with these principles, supporting you in your journey towards optimal health and well-being.

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