Olympic-Level Tips for Mitochondrial Health

Elite athletes have differences in their mitochondria compared to sedentary individual. Learn how to take your mitochondria to Olympic levels.

Illustration of human cells and mitochondria
What to know
  • Research suggests that elite athletes have higher mitochondrial density and superior function than sedentary individuals.

  • Regular exercise, including aerobic and strength training, boosts mitochondrial function, increases VO2 max, and enhances energy production.

  • A healthy diet and good quality sleep are critical for optimal mitochondrial function.

  • Mitopure® supplementation, containing Urolithin A, promotes mitophagy and supports mitochondrial health, improving muscle strength and endurance.

Imagine having the boundless energy of an Olympic athlete, feeling ready to tackle your day with vigor and vitality. The secret lies in the tiny powerhouses within your cells—your mitochondria. These microscopic energy factories are responsible for converting the food you eat into the fuel your body needs to feel its best and perform at its peak. They’re also critical for keeping our cells healthy and well-functioning as we age.

Examining the mitochondria of elite athletes

Elite athletes exhibit remarkable differences in their mitochondrial structure and function compared to sedentary individuals, which significantly impacts their athletic performance. Research indicates that athletes have higher mitochondrial density and superior mitochondrial quality, enhancing muscle respiratory capacity and efficiency during exercise.[1]

Through consistent and intense training, athletes enhance their mitochondrial density and function, allowing their cells to produce energy more efficiently.1 This improved mitochondrial performance not only boosts their athletic capabilities but also contributes to better overall health and increased resilience to stress.

Olympic swimmer

5 tips to give your mitochondria and Olympic edge

If you’re not an elite Olympian or even an athlete, you can still care for your mitochondria to boost energy, improve endurance, and enhance your overall health. Let’s explore five easy ways to take better care of your mitochondria so you can power through life like a champion!

Eat a nutritious diet

Your mitochondria need to be fueled with a diet rich in whole foods, including plenty of fruits, vegetables, lean proteins, and healthy fats. Foods high in antioxidants, especially pomegranates, berries, nuts, and leafy greens, help protect mitochondria from oxidative stress and support their optimal function.[2]

At the same time, minimizing the intake of calorie-dense, nutrient-poor foods like fried foods, fast food, and ultra-processed foods and beverages like soda, baked goods, and other snack foods can help make room for all of the mitochondrial-supportive foods.

Embrace regular exercise

Engaging in physical activity, including aerobic exercises like jogging, cycling, or swimming, as well as strength training, can significantly boost mitochondrial function.1 Exercise also helps to increase your V02 max, a longevity biomarker that measures your aerobic capacity.

Regular exercise increases the production of new mitochondria, stimulates mitophagy, and enhances their efficiency, ensuring your body has a steady supply of energy.

If you’re new to exercise, start slow and do something you love, so you’ll want to keep doing it. Then, you can build it up from there.

Get your beauty rest

Quality sleep is critical for recovery, and it is also a must for mitochondrial maintenance and repair. Aim for 7-9 hours of sleep per night to ensure your body has enough time to restore and rejuvenate its cellular powerhouses. Sticking to a regular sleep schedule and a relaxing bedtime routine can help you achieve a more restful sleep.

To help get better rest, start with a wind-down routine that doesn’t involve screens. Turn off all screens within an hour of bedtime and instead try reading, taking a warm bath, or meditating to prime yourself for bed. This will help relax your body and mind and enable you to fall asleep faster, improving your overall sleep quality.

Almost empty plate

Consider intermittent fasting or calorie restriction

Practicing fasting or calorie restriction can also support mitochondrial function. Studies suggest that these practices can stimulate mitochondrial turnover, also called mitophagy.[3]

There are many intermittent fasting methods out there which can range from a daily 12-hour fast to a more extended 24-hour fast. Always speak to your doctor before starting a fasting regimen to ensure it’s safe for you.

Nutrional supplementation

If you have a varied diet like most of us do, taking a targeted mitochondrial health supplement can provide peace of mind. Mitopure® contains Urolithin A, a unique compound that supports mitochondrial health by inducing mitophagy, a process of removing damaged, old mitochondria and recycling them into newer, healthier versions of themselves.

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While Urolithin A is a postbiotic nutrient (a metabolite produced via our gut microbiome), only 40% of people are able to make enough of this powerful molecule.

Mitopure has been clinically proven to

  • Increase cellular energy[4]
  • Improve muscle strength by 12% after 16 weeks[5]
  • Improve muscle endurance by 17% after 8 weeks[6]

Because of this, direct supplementation via an evidence-based supplement like Mitopure is the only way to ensure you receive a clinically effective dose of Urolthin A for mitochondrial health.

By following these five simple tips, you’ll be on your way to Olympian status in no time, enjoying the benefits of sustained energy and improved overall health.

Authors

Melissa Mitri, MS, RD

Dietitian-Nutritionist, and Health Content Writer

Jen Scheinman, MS, RDN, CDN

Reviewed by

Senior Manager of Nutrition Affairs

References

  1. Jacobs, R., & Lundby, C. (2013). Mitochondria express enhanced quality as well as quantity in association with aerobic fitness across recreationally active individuals up to elite athletes.. Journal of applied physiology, 114 3, 344-50 . https://doi.org/10.1152/japplphysiol.01081.2012.

  2. Zanini, G., Gaetano, A., Selleri, V., Savino, G., Cossarizza, A., Pinti, M., Mattioli, A., & Nasi, M. (2021). Mitochondrial DNA and Exercise: Implications for Health and Injuries in Sports. Cells, 10. https://doi.org/10.3390/cells10102575.

  3. Mehrabani S, Bagherniya M, Askari G, Read MI, Sahebkar A. The effect of fasting or calorie restriction on mitophagy induction: a literature review. J Cachexia Sarcopenia Muscle. 2020 Dec;11(6):1447-1458. doi: 10.1002/jcsm.12611. Epub 2020 Aug 27. PMID: 32856431; PMCID: PMC7749612.

  4. Andreux, P.A., Blanco-Bose, W., Ryu, D. et al. The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans. Nat Metab 1, 595–603 (2019). https://doi.org/10.1038/s42255-019-0073-4

  5. Singh A, D'Amico D, Andreux PA, Fouassier AM, Blanco-Bose W, Evans M, Aebischer P, Auwerx J, Rinsch C. Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults. Cell Rep Med. 2022 May 17;3(5):100633. doi:

  6. Liu S, D’Amico D, Shankland E, et al. Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults: A Randomized Clinical Trial. JAMA Netw Open. 2022;5(1):e2144279. doi:10.1001/jamanetworkopen.2021.44279

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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. References: *Nutrition studies: 500mg Mitopure® have been shown to (1) induce gene expression related to mitochondria function and metabolism and (2) increase the strength of the hamstring leg muscle in measures of knee extension and flexion in overweight 40-65 year olds. Data from two randomized double-blind placebo-controlled human clinical trials. **Nutrition NOURISH Study: 500mg Mitopure® have been shown to deliver at least 6 times higher Urolithin A plasma levels over 24 hours (area under the curve) than 8 ounces (240ml) of pomegranate juice in a randomized human clinical trial.

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© 2024